Peculiar Morphology of Stones in Primary Hyperoxaluria
Authors:
- Michel DaudonMichel Daudon
- Paul JungersPJPaul Jungers
- Dominique BazinDBDominique Bazin
- 3 July 2008
- journal article
- letter
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 359 (1) , 100-102
Abstract
Primary hyperoxaluria type 1 is a rare inherited disease leading to recurrent nephrolithiasis, nephrocalcinosis, systemic oxalosis, and renal failure, ultimately requiring combined kidney and liver transplantation.1,2 Because of the rarity of this disorder, the diagnosis is often missed or delayed by several years, especially when the disease first manifests in adulthood, thus depriving patients of the benefits of therapeutic measures that have been instituted in a timely manner.2,3 Therefore, any method allowing early diagnosis is eagerly awaited.4 However, although nephrolithiasis is the revealing symptom in the great majority of patients with this disease at any age, until now little attention has been paid to the analysis of stones as a possible diagnostic tool.Keywords
This publication has 4 references indexed in Scilit:
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- Diagnostic and therapeutic strategies in hyperoxaluria: a plea for early interventionNephrology Dialysis Transplantation, 2004
- The Primary HyperoxaluriasJournal of the American Society of Nephrology, 2001
- Primary hyperoxaluria type 1Kidney International, 1999