A role for Numb in p53 stabilization
Authors:
Open Access
- 1 January 2008
- journal article
- review article
- Published by Springer Nature in Genome Biology
- Vol. 9 (5) , 221
Abstract
The cell-fate determinant Numb has recently been shown to help activate the tumor suppressor protein p53. Loss of Numb in breast cancers would result, therefore, in both the activation of the potential oncogene Notch and the diminution of tumor suppression by p53.Keywords
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