Calcineurin Localizes to the Hyphal Septum in Aspergillus fumigatus : Implications for Septum Formation and Conidiophore Development
- 1 September 2008
- journal article
- Published by American Society for Microbiology in Eukaryotic Cell
- Vol. 7 (9) , 1606-1610
Abstract
A functional calcineurin A fusion to enhanced green fluorescent protein (EGFP), CnaA-EGFP, was expressed in the Aspergillus fumigatus Δ cnaA mutant. CnaA-EGFP localized in actively growing hyphal tips, at the septa, and at junctions between the vesicle and phialides in an actin-dependent manner. This is the first study to implicate calcineurin in septum formation and conidiophore development of a filamentous fungus.Keywords
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