Evaluation of a GDNF-eluting nanofibrous PCL conduit in a mouse model of peripheral nerve injury
Open Access
- 29 April 2026
- journal article
- Published by Royal Society of Chemistry (RSC) in RSC Advances
- Vol. 16 (25) , 23177-23189
Abstract
An electrospun nerve guidance conduit comprised of aligned, growth factor-loaded nanofibres and a fibrin hydrogel promotes peripheral nerve regeneration, demonstrating comparable axonal growth to the nerve graft in a severe injury model.Keywords
Funding Information
- Engineering and Physical Sciences Research Council (EP/L01646X/1)
- Engineering and Physical Sciences Research Council (EP/S022201/1)
- Engineering and Physical Sciences Research Council (EP/X525649/1)
- Leverhulme Trust (SRF\R1\221053)
- Royal Society (SRF\R1\221053)
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