A Simple Approach to the Synthesis of Fluoren-9-Ones
Authors:
- 1 June 1995
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 25 (11) , 1751-1760
Abstract
Cyclohexene-l-Carboxylic acid (I) undergoes reaction with various aromatic substrates (2a-i) in presence of Polyphosphoric acid (PPA) at 100[ddot]c to give cis-1,2,3,4,4a,9a - hexahydrofluoren-9-ones (3a-i) in good yield. Dehydrogenation of (3a-i) with selenium powder afforded corresponding fluoren-9-ones (4a-i) in high yield.Keywords
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