Some properties of the denervated anterior gracilis muscle of the rat

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Abstract
. Microdrops of acetylcholine (ACh) were topically applied to denervated, mammalian skeletal musclein vivo, and ACh‐evoked depolarization and contracture were recorded simultaneously. . Contracture tension was directly proportional to the degree of ACh‐elicited depolarization. . Atropine and (+)‐tubocurarine increased the amount of ACh required to produce a given amount of depolarization, but these anticholinergic agents did not alter the relationship between the degree of ACh‐evoked depolarization and contracture tension. . Topically applied catecholamines did not produce either depolarization or contracture, despite the fact that parenterally administered catecholamines elicited both responses.

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