Gold Nanoparticles-Decorated Silicon Nanowires as Highly Efficient Near-Infrared Hyperthermia Agents for Cancer Cells Destruction
- 8 March 2012
- journal article
- letter
- Published by American Chemical Society (ACS) in Nano Letters
- Vol. 12 (4) , 1845-1850
Abstract
Near-infrared (NIR) hyperthermia agents are of current interest because they hold great promise as highly efficacious tools for cancer photothermal therapy. Although various agents have been reported, a practical NIR hyperthermia agent is yet unavailable. Here, we present the first demonstration that silicon nanomaterials-based NIR hyperthermia agent, that is, gold nanoparticles-decorated silicon nanowires ([email protected]), is capable of high-efficiency destruction of cancer cells. [email protected] are found to possess strong optical absorbance in the NIR spectral window, producing sufficient heat under NIR irradiation. [email protected] are explored as novel NIR hyperthermia agents for photothermal ablation of tumor cells. In particular, three different cancer cells treated with [email protected] were completely destructed within 3 min of NIR irradiation, demonstrating the exciting potential of [email protected] for NIR hyperthermia agents.Keywords
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