Reversal of endothelial dysfunction reduces white matter vulnerability in cerebral small vessel disease in rats
Authors:
- Rikesh M. RajaniRRRikesh M. Rajani
- Sophie QuickSQSophie Quick
- Silvie R. RuigrokSRSilvie R. Ruigrok
- Delyth GrahamDGDelyth Graham
- Sarah E. HarrisSHSarah E. Harris
- Benjamin F. J. VerhaarenBVBenjamin F. J. Verhaaren
- Sudha SeshadriSSSudha Seshadri
- Anna F. DominiczakADAnna F. Dominiczak
- Colin SmithCSColin Smith
- Joanna M. WardlawJWJoanna M. Wardlaw
- 4 July 2018
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science Translational Medicine
- Vol. 10 (448)
Abstract
Endothelial cell–stabilizing drugs reverse white matter pathology in a rat model of cerebral small vessel disease.Keywords
Funding Information
- Medical Research Council (PhD fellowship)
- Fondation Leducq (16 CVD 05)
- BBSRC (MR/K026992/1)
- Alzheimer’s Research UK (ARUK-PPG2016A-3)
- BHF Centre of Research Excellence, Glasgow (RE/13/5/30177)
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