Therapeutic opportunities for the treatment of NASH with genetically validated targets

This publication has 71 references indexed in Scilit:

• Chronic overexpression of PNPLA3I148M in mouse liver causes hepatic steatosis
  Journal of Clinical Investigation, 2012
• Paradoxical Lower Serum Triglyceride Levels and Higher Type 2 Diabetes Mellitus Susceptibility in Obese Individuals with the PNPLA3 148M Variant
  PLOS ONE, 2012
• Mammalian Triacylglycerol Metabolism: Synthesis, Lipolysis, and Signaling
  Chemical Reviews, 2011
• Patatin-Like Phospholipase Domain-Containing 3/Adiponutrin Deficiency in Mice Is Not Associated with Fatty Liver Disease†,‡
  Hepatology, 2010
• A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis
  Journal of Biological Chemistry, 2010
• Cideb, an ER- and Lipid Droplet-Associated Protein, Mediates VLDL Lipidation and Maturation by Interacting with Apolipoprotein B
  Cell Metabolism, 2009
• Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
  Nature Genetics, 2008
• The role of mitochondrial glycerol-3-phosphate acyltransferase-1 in regulating lipid and glucose homeostasis in high-fat diet fed mice
  Biochemical and Biophysical Research Communications, 2008
• Caenorhabditis elegans mboa-7, a Member of the MBOAT Family, Is Required for Selective Incorporation of Polyunsaturated Fatty Acids into Phosphatidylinositol
  Molecular Biology of the Cell, 2008
• Cideb Regulates Diet-Induced Obesity, Liver Steatosis, and Insulin Sensitivity by Controlling Lipogenesis and Fatty Acid Oxidation
  Diabetes, 2007