Figure S4 from MYC Induces Oncogenic Stress through RNA Decay and Ribonucleotide Catabolism in Breast Cancer

Authors:

JMJitendra K. Meena
Jitendra K. Meena
JWJarey H. Wang
Jarey H. Wang
NNNicholas J. Neill
Nicholas J. Neill
DKDianne Keough
Dianne Keough
Nagireddy Putluri
Nagireddy Putluri
Panagiotis Katsonis
Panagiotis Katsonis
AKAmanda M. Koire
Amanda M. Koire
HLHyemin Lee
Hyemin Lee
EBElizabeth A. Bowling
Elizabeth A. Bowling
STSiddhartha Tyagi
Siddhartha Tyagi
MOMayra Orellana
Mayra Orellana
RDRocio Dominguez-Vidaña
Rocio Dominguez-Vidaña

Open Access

Publisher website

Google Scholar

17 June 2026

other
Published by American Association for Cancer Research (AACR)

DOI:10.1158/2159-8290.32698626

Abstract

Figure S4 shows DIS3L mutation in human tumors, evolutionary action score of tumor-derived mutation in DIS3L, genomic alteration of MYC and DIS3L in human breast cancer, expression of DIS3L mRNA in human breast tumors, and expression of genes in ribonucleotide catabolism and synthesis upon DIS3L knockdown.

Keywords

RIBONUCLEOTIDE CATABOLISM
BREAST CANCER
INDUCES ONCOGENIC
ONCOGENIC STRESS
RNA DECAY
HUMAN BREAST
MYC INDUCES
CANCER FIGURE
BREAST TUMORS
HUMAN TUMORS