Plausible origins of homochirality in the amino acid catalyzed neogenesis of carbohydrates
- 1 March 2005
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 15,p. 2047-2049
Abstract
The intrinsic ability of amino acids to catalyze the asymmetric formation of carbohydrates, which enzymes have mediated for millions of years, with significant amplification of enantiomeric excess suggests a plausible ancient catalytic process for the evolution of homochirality.Keywords
This publication has 32 references indexed in Scilit:
- Chiral amplification by polypeptides and its relevance to prebiotic catalysisChemical Communications, 2004
- The Direct Amino Acid-Catalyzed Asymmetric Incorporation of Molecular Oxygen to Organic CompoundsJournal of the American Chemical Society, 2004
- Amplification of Enantiomeric Excess in a Proline‐Mediated ReactionAngewandte Chemie International Edition, 2004
- Prebiotic Amino Acids as Asymmetric CatalystsScience, 2004
- Enantiomeric Excesses in Meteoritic Amino AcidsScience, 1997
- Highly Enantioselective Catalytic Asymmetric Automultiplication of Chiral Pyrimidyl AlcoholJournal of the American Chemical Society, 1996
- Asymmetric autocatalysis and amplification of enantiomeric excess of a chiral moleculeNature, 1995
- Origins of homochiralityNature, 1995
- Chemical evolution: Origin of biomolecular chiralityNature, 1985
- On spontaneous asymmetric synthesisBiochimica et Biophysica Acta, 1953