Molecular Characterization ofCandida africanain Genital Specimens in Shanghai, China
Open Access
- 19 November 2015
- journal article
- research article
- Published by Hindawi Limited in BioMed Research International
- Vol. 2015, 1-5
Abstract
Candida africana, an emerging yeast pathogen, is closely related toCandida albicansand most commonly involved in vulvovaginal candidiasis (VVC). However, its prevalence in candidal balanoposthitis is still unclear. In this study, the prevalence ofC. africanain both candidal balanoposthitis and VVC in a sexually transmitted diseases (STD) clinic in Shanghai, China, was analyzed, and the molecular characterization and susceptible profiles ofC. africanaisolates were investigated. As results,C. africanawas only isolated in 5 out of 79 (6.3%) cases of candidal balanoposthitis rather than cases with vulvovaginal candidiasis. Among them, 4 out of 5 isolates share the same genotype of DST 782 with an isolate from vaginal swab in Japan published previously. AllC. africanaisolates were susceptible to amphotericin B, flucytosine, fluconazole, itraconazole, voriconazole, posaconazole, caspofungin, and micafungin.Keywords
Funding Information
- Medical Specialty Discipline Construction Program B of Shanghai (ZK2012B18)
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