Polymer-wrapped single-walled carbon nanotubes: a transformation toward better applications in healthcare
- 28 March 2018
- journal article
- review article
- Published by Springer Nature in Drug Delivery and Translational Research
- Vol. 9 (2) , 578-594
Abstract
Carbon nanotubes (CNTs) possess outstanding properties that could be useful in several technological, drug delivery, and diagnostic applications. However, their unique physical and chemical properties are hindered due to their poor solubility. This article review’s the different ways and means of solubility enhancement of single-wall carbon nanotubes (SWNTs). The advantages of SWNTs over the multi-walled carbon nanotubes (MWNTs) and the method of non-covalent modification for solubility enhancement has been the key interest in this review. The review also highlights a few examples of dispersant design. The review includes some interesting utility of SWNTs being wrapped with polymer especially in biological media that could mediate proper drug delivery to target cells. Further, the use of wrapped SWNTs with phospholipids, nucleic acid, and amphiphillic polymers as biosensors is of research interest. The review aims at summarizing the developments relating to wrapped SWNTs to generate further research prospects in healthcare.Keywords
Funding Information
- Ministry of Higher Education, Malaysia ((600-RMIA/FRGS 5/3 (4/2014)))
This publication has 98 references indexed in Scilit:
- Targeting colorectal cancer cells with single-walled carbon nanotubes conjugated to anticancer agent SN-38 and EGFR antibodyBiomaterials, 2013
- Binding Affinities and Thermodynamics of Noncovalent Functionalization of Carbon Nanotubes with SurfactantsLangmuir, 2013
- Near Infrared Imaging and Photothermal Ablation of Vascular Inflammation Using Single‐Walled Carbon NanotubesJournal of the American Heart Association, 2012
- Antimicrobial Activity of Single-Walled Carbon Nanotubes: Length EffectLangmuir, 2010
- Relevance of Weak Hydrogen Bonds in the Conformation of Organic Compounds and Bioconjugates: Evidence from Recent Experimental Data and High-Levelab InitioMO CalculationsChemical Reviews, 2010
- Conjugated Polymer Poly(2-methoxy-5-(3′,7′- dimethyloctyloxy)-1,4-phenylenevinylene) Modification on Carbon Nanotubes with Assistance of Supercritical Carbon Dioxide: Chemical Interaction, Solubility, and Light EmissionThe Journal of Physical Chemistry C, 2010
- Interactions of single-wall carbon nanotubes with endothelial cellsNanomedicine: Nanotechnology, Biology and Medicine, 2010
- Drug Delivery with Carbon Nanotubes forIn vivoCancer TreatmentCancer Research, 2008
- Cancer Cell Imaging and Photothermal Therapy in the Near-Infrared Region by Using Gold NanorodsJournal of the American Chemical Society, 2006
- Individually Suspended Single-Walled Carbon Nanotubes in Various SurfactantsNano Letters, 2003