Rewiring cell signalling pathways in pathogenic mtDNA mutations
Open Access
- 1 May 2022
- journal article
- review article
- Published by Elsevier in Trends in Cell Biology
- Vol. 32 (5) , 391-405
Abstract
No abstract availableKeywords
Funding Information
- Action Medical Research (GN2158)
- Agencia Nacional de Investigación y Desarrollo
- Agenția Națională pentru Cercetare și Dezvoltare
- Medical Research Council (MR/RO15759/1)
This publication has 116 references indexed in Scilit:
- Mitochondrial autophagy in cells with mtDNA mutations results from synergistic loss of transmembrane potential and mTORC1 inhibitionHuman Molecular Genetics, 2011
- NARP mutation and mtDNA depletion trigger mitochondrial biogenesis which can be modulated by selenite supplementationThe International Journal of Biochemistry & Cell Biology, 2011
- Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cellsProceedings of the National Academy of Sciences, 2010
- Reactive Oxygen Species-generating Mitochondrial DNA Mutation Up-regulates Hypoxia-inducible Factor-1α Gene Transcription via Phosphatidylinositol 3-Kinase-Akt/Protein Kinase C/Histone Deacetylase PathwayJournal of Biological Chemistry, 2009
- Inhibition of mitochondrial fission favours mutant over wild-type mitochondrial DNAHuman Molecular Genetics, 2009
- ROS-Generating Mitochondrial DNA Mutations Can Regulate Tumor Cell MetastasisScience, 2008
- Visualizing common deletion of mitochondrial DNA-augmented mitochondrial reactive oxygen species generation and apoptosis upon oxidative stressBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2006
- Mitochondrial DNA mutations in human diseaseNature Reviews Genetics, 2005
- Leber's hereditary optic neuropathy with 14484 mutation in Central Java, IndonesiaJournal of Human Genetics, 2003
- Exercise Intolerance Due to Mutations in the CytochromebGene of Mitochondrial DNANew England Journal of Medicine, 1999