Association of Variation in Contrast Volume With Acute Kidney Injury in Patients Undergoing Percutaneous Coronary Intervention

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Abstract
Acute kidney injury (AKI) after percutaneous coronary intervention (PCI) is common, occurring in 7% of patients,1,2 but is a severely morbid and costly event that increases the risk of dialysis and mortality.1-4 Because hydration has modest benefit and administration of sodium bicarbonate and N-acetylcysteine has not proved to be effective in preventing AKI,5-7 reducing contrast volume may be the most effective strategy for preventing AKI.8

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