Nonylphenol Toxicity: Exposure, Mode of Action, Toxic Effects
Authors:
Open Access
- 1 October 2024
- journal article
- Published by Egyptian Knowledge Bank in Journal of Current Veterinary Research
- Vol. 6 (2) , 57-71
Abstract
Nonylphenol (NPL) is concerned as a substance that may disrupt human endocrine systems. NPL is extensively prevalent in the environment which could disrupt the nervous system, immune system, reproduction. Its high hydrophobicity, makes NPL can withstand environmental conditions for an extended period particularly those in soil. Determining NPL risk depends up on the exposure circumstances including exposure pathways, exposure time, and exposure concentrations. It's critical to comprehend these concerns to evaluate the risk for human. NPL contaminates the environment through soil, and wastewater effluents causing its toxicity. Hence, determining origin, fate and harmful impact of NPL, besides elimination of it appears to be a top priority. NPL can be treated using microbiological and physicochemical techniques. Meanwhile, the fact that microbial techniques are environmentally friendly makes them popular. This review shows NPL toxicity, fate, and the ways for elimination from the environment.Keywords
This publication has 49 references indexed in Scilit:
- Palliative effect of dietary common sage leaves against toxic impacts of nonylphenol in Mirror carp (Cyprinus carpio var specularis): Growth, gene expression, immune-antioxidant status, and histopathological alterationsAquaculture Reports, 2022
- Palliative effects of zinc sulfate against the immunosuppressive, hepato- and nephrotoxic impacts of nonylphenol in Nile tilapia (Oreochromis niloticus)Aquaculture, 2019
- An integrated modelling framework and a modified method for evaluating non-carcinogenic health risks from nonylphenol-contaminated food consumption in Long An, VietnamEnvironmental Science and Pollution Research, 2018
- Endocrine disruption, oxidative stress, and testicular damage induced by 4-nonylphenol in Clarias gariepinus: the protective role of Cydonia oblongaFish Physiology and Biochemistry, 2017
- In vitro assessment of ROS on motility of epididymal sperm of male rat exposed to intraperitoneal administration of nonylphenolAsian Pacific Journal of Reproduction, 2015
- Toxic effect of gestational exposure to nonylphenol on F1 male ratsBirth Defects Research Part B: Developmental and Reproductive Toxicology, 2010
- Evaluation of genotoxicity and effects on reproduction of nonylphenol in Oreochromis niloticus (Pisces: cichlidae)Ecotoxicology, 2008
- The Effects of Nonylphenol and Octylphenol on Embryonic Development of Sea Urchin (Paracentrotus lividus)Archives of Environmental Contamination and Toxicology, 2007
- A repeated 28-day oral dose toxicity study of nonylphenol in rats, based on the ‘Enhanced OECD Test Guideline 407’ for screening of endocrine-disrupting chemicalsArchives of Toxicology, 2006
- Zebrafish as a model for developmental neurotoxicity testingBirth Defects Research Part A: Clinical and Molecular Teratology, 2006