Efficient enzymatic preparation of (+)- and (-)-corey lactone derivatives.

Authors:
  • TSTsutomu Sugahara
    Tsutomu Sugahara
  • ISIkuko Satoh
    Ikuko Satoh
  • OYOsamu Yamada
    Osamu Yamada
  • STSeiichi Takano
    Seiichi Takano
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Abstract
Two pairs of Corey lactone derivatives, (+)-1, (-)-2 and (+)-3, (-)-4 have been efficiently prepared in high optical purity by enzymatic esterification and enzymatic hydrolysis catalyzed by lipases from Pseudomonas sp.