Solution structure of an ultra-stable single-chain insulin analog connects protein dynamics to a novel mechanism of receptor binding
Open Access
- 1 January 2018
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 293 (1) , 69-88
Abstract
No abstract availableKeywords
Funding Information
- National Institutes of Health (R01 DK040949, R01 DK069764, 5T32GM007250–38, 1F30DK104618–01)
- American Diabetes Association (7–13-IN-31, 1–08-RA-149)
- National Health and Medical Research Council (APP1058233)
This publication has 99 references indexed in Scilit:
- Computational studies of molecular machines: the ribosomeCurrent Opinion in Structural Biology, 2012
- CHARMM Additive All-Atom Force Field for Carbohydrate Derivatives and Its Utility in Polysaccharide and Carbohydrate–Protein ModelingJournal of Chemical Theory and Computation, 2011
- Life's demons: information and order in biologyEMBO Reports, 2011
- Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretionDiabetologia, 2010
- TALOS+: a hybrid method for predicting protein backbone torsion angles from NMR chemical shiftsJournal of Biomolecular NMR, 2009
- Optimisation of NMR dynamic models I. Minimisation algorithms and their performance within the model-free and Brownian rotational diffusion spacesJournal of Biomolecular NMR, 2007
- Ensemble Refinement of Protein Crystal Structures: Validation and ApplicationStructure, 2007
- Canonical sampling through velocity rescalingThe Journal of Chemical Physics, 2007
- NMRPipe: A multidimensional spectral processing system based on UNIX pipesJournal of Biomolecular NMR, 1995
- Time-dependent distance restraints in molecular dynamics simulationsChemical Physics Letters, 1989