Machine Learning and Image Processing Enabled Evolutionary Framework for Brain MRI Analysis for Alzheimer’s Disease Detection

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Abstract
Alzheimer’s disease is characterized by the presence of abnormal protein bundles in the brain tissue, but experts are not yet sure what is causing the condition. To find a cure or aversion, researchers need to know more than just that there are protein differences from the usual; they also need to know how these brain nerves form so that a remedy may be discovered. Machine learning is the study of computational approaches for enhancing performance on a specific task through the process of learning. This article presents an Alzheimer’s disease detection framework consisting of image denoising of an MRI input data set using an adaptive mean filter, preprocessing using histogram equalization, and feature extraction by Haar wavelet transform. Classification is performed using LS-SVM-RBF, SVM, KNN, and random forest classifier. An adaptive mean filter removes noise from the existing MRI images. Image quality is enhanced by histogram equalization. Experimental results are compared using parameters such as accuracy, sensitivity, specificity, precision, and recall.

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