Synthesis of Lysophosphatidylglycerol, a Bioactive Lipid

Authors:
Preprint
Publisher website
Google Scholar
Abstract
Lysophosphatidylglycerol (Lyso-PG) is an important membrane lipid that has critical roles in immune regulation and tissue repair. However, precise mechanisms of how lyso-PG does this are yet to be completely characterized due to its limited commercial availability. Here, an efficient stereoselective synthesis of C18:1 lyso-PG is reported, and this new lipid probe should help interrogate cellular and other physiological functions of lyso-PG.
Funding Information
  • EMBO (SSK)