In vitro studies on the modification of low-dose hyper-radiosensitivity in prostate cancer cells by incubation with genistein and estradiol
Authors:
Open Access
- 14 July 2008
- journal article
- research article
- Published by Springer Nature in Radiation Oncology
- Vol. 3 (1) , 19
Abstract
As the majority of prostate cancers (PC) express estrogen receptors, we evaluated the combination of radiation and estrogenic stimulation (estrogen and genistein) on the radiosensitivity of PC cells in vitro.Keywords
This publication has 43 references indexed in Scilit:
- Soy isoflavones enhance radiotherapy in a metastatic prostate cancer modelInternational Journal of Cancer, 2007
- Comparative effects of DHEA vs. testosterone, dihydrotestosterone, and estradiol on proliferation and gene expression in human LNCaP prostate cancer cellsAmerican Journal of Physiology-Endocrinology and Metabolism, 2005
- Genistein induces cell growth inhibition in prostate cancer through the suppression of telomerase activityInternational Journal of Urology, 2005
- A Concentrated Aglycone Isoflavone Preparation (GCP) That Demonstrates Potent Anti-Prostate Cancer ActivityIn vitroandIn vivoClinical Cancer Research, 2004
- Methylation and Inactivation of Estrogen, Progesterone, and Androgen Receptors in Prostate CancerJNCI: Journal of the National Cancer Institute, 2002
- Expression of Estrogen Receptor (ER–α and ER–β) mRNA in Human Prostate CancerEuropean Urology, 2001
- Protein tyrosine kinase inhibitor, genistein, enhances apoptosis and cell cycle arrest in K562 cells treated with γ-irradiationCancer Letters, 2000
- Expression of Estrogen Receptor α and β mRNAs in Prostate Cancers Treated with Leuprorelin AcetateEuropean Urology, 2000
- Genistein‐induced upregulation of p21WAF1, downregulation of cyclin B, and induction of apoptosis in prostate cancer cellsNutrition and Cancer, 1998
- Radiosensitivity of human breast cancer cell lines of different hormonal responsiveness. Modulatory effects of oestradiolInternational Journal of Radiation Biology, 1996