Optimal control of Alzheimer’s disease model via multi-target combination therapy
- 11 March 2026
- journal article
- Published by Elsevier in Journal of Theoretical Biology
- Vol. 625, 112425
Abstract
No abstract availableKeywords
Funding Information
- China Postdoctoral Science Foundation (2024M752990)
- Shanxi Scholarship Council of China (2022-151)
- National Natural Science Foundation of China (12201582)
- National Natural Science Foundation of China (12401656)
This publication has 87 references indexed in Scilit:
- A confidence ellipse analysis for stochastic dynamics model of Alzheimer's diseaseNonlinear Dynamics, 2023
- Cost-effectiveness of Aducanumab and Donanemab for Early Alzheimer Disease in the USJAMA Neurology, 2022
- Amyloid-Related Imaging Abnormalities in 2 Phase 3 Studies Evaluating Aducanumab in Patients With Early Alzheimer DiseaseJAMA Neurology, 2021
- Model‐Informed Drug Development: Connecting the Dots With a Totality of Evidence Mindset to Advance TherapeuticsClinical Pharmacology & Therapeutics, 2021
- Stability analysis of a steady state of a model describing Alzheimer’s disease and interactions with prion proteinsJournal of Mathematical Biology, 2018
- Amyloid β oligomers in Alzheimer’s disease pathogenesis, treatment, and diagnosisActa Neuropathologica, 2015
- Convergence of the forward-backward sweep method in optimal controlComputational Optimization and Applications, 2012
- Determining Important Parameters in the Spread of Malaria Through the Sensitivity Analysis of a Mathematical ModelBulletin of Mathematical Biology, 2008
- Optimal control of an HIV immunology modelOptimal Control Applications and Methods, 2002
- Cost-effectiveness of the Transdermal Nicotine Patch as an Adjunct to Physicians' Smoking Cessation CounselingJAMA, 1996