Doxorubicin loaded ferritin nanoparticles for ferroptosis enhanced targeted killing of cancer cells
Open Access
- 10 September 2019
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in RSC Advances
- Vol. 9 (49) , 28548-28553
Abstract
DOX loaded ferritin selectively induces ferroptosis enhanced killing of transferrin receptor 1 overexpressed cancer cells.Keywords
Funding Information
- National Natural Science Foundation of China (31671035, 51803082, 31971316)
- Jiangsu Provincial Commission of Health and Family Planning (LGY2017088, H2018069, H2017031)
This publication has 33 references indexed in Scilit:
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell DeathCell, 2012
- Modulatory profiling identifies mechanisms of small molecule-induced cell deathProceedings of the National Academy of Sciences, 2011
- Doxorubicin pathwaysPharmacogenetics and Genomics, 2011
- Doxorubicin as a Molecular Nanotheranostic Agent: Effect of Doxorubicin Encapsulation in Micelles or Nanoemulsions on the Ultrasound-Mediated Intracellular Delivery and Nuclear TraffickingMolecular Pharmaceutics, 2010
- Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell DeathCell Metabolism, 2008
- Synthetic Lethal Screening Identifies Compounds Activating Iron-Dependent, Nonapoptotic Cell Death in Oncogenic-RAS-Harboring Cancer CellsChemistry & Biology, 2008
- RAS–RAF–MEK-dependent oxidative cell death involving voltage-dependent anion channelsNature, 2007
- What Is Responsible for the Initiating Chemistry of Iron-Mediated Lipid Peroxidation: An UpdateChemical Reviews, 2007
- Doxorubicin-induced reactive oxygen species generation and intracellular Ca2+increase are reciprocally modulated in rat cardiomyocytesExperimental & Molecular Medicine, 2006
- A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicinBiochemical Pharmacology, 1999