Complexity and pitfalls of mass spectrometry-based targeted metabolomics in brain research
Authors:
- David P. EnotDEDavid P. Enot
- Guido DallmannGDGuido Dallmann
- Lisa KörnerLKLisa Körner
- Verena ForcherVFVerena Forcher
- Peter EnohPEPeter Enoh
- Therese KoalTKTherese Koal
- Matthias KellerMKMatthias Keller
- Hans-Peter DeignerHDHans-Peter Deigner
- 1 November 2010
- journal article
- research article
- Published by Elsevier in Analytical Biochemistry
- Vol. 406 (2) , 124-131
Abstract
No abstract availableKeywords
Funding Information
- European Commission (LSHM-CT-2006-036534)
This publication has 39 references indexed in Scilit:
- A metabolomic study of the CRND8 transgenic mouse model of Alzheimer's diseaseNeurochemistry International, 2010
- Analyzing the Effects of Psychotropic Drugs on Metabolite Profiles in Rat Brain Using1H NMR SpectroscopyJournal of Proteome Research, 2009
- Quantitation of small molecules using high‐resolution accurate mass spectrometers – a different approach for analysis of biological samplesRapid Communications in Mass Spectrometry, 2009
- Which Human Metabolites Have We MIST? Retrospective Analysis, Practical Aspects, and Perspectives For Metabolite Identification and Quantification in Pharmaceutical DevelopmentChemical Research in Toxicology, 2009
- Metabonomic Characterization of the 3-Nitropropionic Acid Rat Model of Huntington’s DiseaseNeurochemical Research, 2009
- Analytical strategies for LC–MS-based targeted metabolomicsJournal of Chromatography B, 2008
- AMP‐activated protein kinase phosphorylation in brain is dependent on method of killing and tissue preparationJournal of Neurochemistry, 2007
- Automated sample preparation and purification of homogenized brain tissuesJournal of Pharmaceutical and Biomedical Analysis, 2007
- A metabolomics perspective of human brain tumoursThe FEBS Journal, 2007
- Pre-extraction Sample Handling by Automated Frozen Disruption Significantly Improves Subsequent Proteomic AnalysesJournal of Proteome Research, 2005