Psychosocial Treatment for First-Episode Psychosis: A Research Update
Authors:
- David L. PennDPDavid L. Penn
- Evan J. WaldheterEWEvan J. Waldheter
- Diana O. PerkinsDPDiana O. Perkins
- Kim T. MueserKMKim T. Mueser
- Jeffrey A. LiebermanJLJeffrey A. Lieberman
- 1 December 2005
- journal article
- research article
- Published by American Psychiatric Association Publishing in American Journal of Psychiatry
- Vol. 162 (12) , 2220
Abstract
This article reviews research on psychosocial treatment for first-episode psychosis. PsycINFO and MEDLINE were systematically searched for studies that evaluated psychosocial interventions for first-episode psychosis. Comprehensive (i.e., multielement) treatment approaches show promise in reducing symptoms and hospital readmissions, as well as improving functional outcomes, although few rigorously controlled trials have been conducted. Individual cognitive behavior therapy has shown modest efficacy in reducing symptoms, assisting individuals in adjusting to their illness, and improving subjective quality of life, but it has shown minimal efficacy in reducing relapse. Some controlled research supports the benefits of family interventions, while less controlled research has evaluated group interventions. Adjunctive psychosocial interventions early in psychosis may be beneficial across a variety of domains and can assist with symptomatic and functional recovery. More randomized, controlled trials are needed to evaluate the effectiveness of these interventions, particularly for multielement, group, and family treatments.Keywords
This publication has 81 references indexed in Scilit:
- Progressive Structural Brain Abnormalities and Their Relationship to Clinical OutcomeArchives of General Psychiatry, 2003
- The early stages of schizophrenia: speculations on pathogenesis, pathophysiology, and therapeutic approachesBiological Psychiatry, 2001
- EARLY INTERVENTION IN PSYCHOTIC RELAPSEClinical Psychology Review, 2001
- First-episode non-affective psychosis in a total urban population: a 5-year follow-upSocial Psychiatry and Psychiatric Epidemiology, 2001
- Longitudinal study of brain morphology in first episode schizophreniaBiological Psychiatry, 2001
- The McLean–Harvard first-episode project: 6-month symptomatic and functional outcome in affective and nonaffective psychosisBiological Psychiatry, 2000
- Delay in Treating Schizophrenia May Narrow Therapeutic Window of OpportunityJAMA, 2000
- A pilot study evaluating the effectiveness of individual inpatient cognitive-behavioural therapy in early psychosisSocial Psychiatry and Psychiatric Epidemiology, 1999
- An economic evaluation of schizophrenia-1991Social Psychiatry and Psychiatric Epidemiology, 1995
- Time Course and Biologic Correlates of Treatment Response in First-Episode SchizophreniaArchives of General Psychiatry, 1993