Group B coxsackieviruses readily establish persistent infections in human lymphoid cell lines
Authors:
- D MatteucciDMD Matteucci
- M PagliantiMPM Paglianti
- A M GiangregorioAGA M Giangregorio
- M R CapobianchiMCM R Capobianchi
- F DianzaniFDF Dianzani
- M BendinelliMBM Bendinelli
- 1 November 1985
- journal article
- research article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 56 (2) , 651-654
Abstract
Exposing human lymphoid cell lines to uncloned or recently cloned group B coxsackieviruses results in the frequent establishment of chronically infected cultures. Persistence is maintained by a carrier culture mechanism involving virus spread through the medium and replication among a minority of cells at any given time. These studies provide a model for persistence by highly cytocidal viruses.Keywords
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