Extracellular cathepsin Z signals through the α5 integrin and augments NLRP3 inflammasome activation
Open Access
- 2 December 2021
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 298 (1) , 101459
Abstract
No abstract availableKeywords
Funding Information
- Canadian Institutes of Health Research
- Natural Sciences and Engineering Research Council of Canada
- MS Canada
This publication has 56 references indexed in Scilit:
- Fiji: an open-source platform for biological-image analysisNature Methods, 2012
- Entamoeba histolytica Cysteine Proteinase 5 Binds Integrin on Colonic Cells and Stimulates NFκB-mediated Pro-inflammatory ResponsesJournal of Biological Chemistry, 2010
- Cathepsin X-deficient Gastric Epithelial Cells in Co-culture with MacrophagesJournal of Biological Chemistry, 2010
- Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasomeGut, 2010
- NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystalsNature, 2010
- Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in miceProceedings of the National Academy of Sciences, 2010
- Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilizationNature Immunology, 2008
- The Nalp3 inflammasome is essential for the development of silicosisProceedings of the National Academy of Sciences, 2008
- Silica binding and toxicity in alveolar macrophagesFree Radical Biology and Medicine, 2008
- Toward a better analysis of secreted proteins: the example of the myeloid cells secretomeProteomics, 2007