Establishment of N-Acetylmannosamine (ManNAc) Analogue-Resistant Cell Lines as Improved Hosts for Sialic Acid Engineering Applications

Authors:

MJM.B. Jones
M.B. Jones
JRJ.K. Rhee
J.K. Rhee
SSS.-G. Sampathkumar
S.-G. Sampathkumar
KYK.J. Yarema
K.J. Yarema

3 December 2004

journal article
research article
Published by Wiley in Biotechnology Progress

Vol. 20 (6) , 1674-1682
DOI:10.1021/bp049841q
PMID:15575698

Abstract

Metabolic substrate‐based sialic acid engineering techniques, where exogenously supplied N‐acetylmannosamine (ManNAc) analogues are utilized by the sialic acid biosynthetic pathway, allow the cell su...

Keywords

CELL LINE