Clinical and molecular evidences of epithelial to mesenchymal transition in acquired resistance to EGFR-TKIs
Authors:
- Jin Kyung RhoJRJin Kyung Rho
- Xianhua XuXXXianhua Xu
- Jong Seok LeeJLJong Seok Lee
- Ho Il YoonHYHo Il Yoon
- Choon Taek LeeCLChoon Taek Lee
- Yun Jung ChoiYCYun Jung Choi
- Hye-Ryoun KimHKHye-Ryoun Kim
- Cheol Hyeon KimCKCheol Hyeon Kim
- Jae Cheol LeeJLJae Cheol Lee
- 1 August 2011
- journal article
- case report
- Published by Elsevier in Lung Cancer
- Vol. 73 (2) , 176-182
Abstract
No abstract availableKeywords
This publication has 21 references indexed in Scilit:
- What's your treatment option in a patient with impending respiratory failure due to disseminated lung cancer?Respiratory Medicine CME, 2008
- The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATPProceedings of the National Academy of Sciences, 2008
- Which biomarker predicts benefit from EGFR-TKI treatment for patients with lung cancer?British Journal of Cancer, 2007
- Molecular Predictors of Response to Epidermal Growth Factor Receptor Antagonists in Non–Small-Cell Lung CancerJournal of Clinical Oncology, 2007
- Analysis of Epidermal Growth Factor Receptor Gene Mutation in Patients with Non–Small Cell Lung Cancer and Acquired Resistance to GefitinibClinical Cancer Research, 2006
- Epidermal Growth Factor Receptor Mutations, Small-Molecule Kinase Inhibitors, and Non–Small-Cell Lung Cancer: Current Knowledge and Future DirectionsJournal of Clinical Oncology, 2005
- Acquired Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib Is Associated with a Second Mutation in the EGFR Kinase DomainPLOS Medicine, 2005
- EGF receptor gene mutations are common in lung cancers from “never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinibProceedings of the National Academy of Sciences, 2004
- Determinants of Tumor Response and Survival With Erlotinib in Patients With Non—Small-Cell Lung CancerJournal of Clinical Oncology, 2004
- The role of EGFR inhibitors in nonsmall cell lung cancerCurrent Opinion in Oncology, 2004