How Safe Is Safe for Marine Toxins Monitoring?

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Abstract
Current regulation for marine toxins requires a monitoring method based on mass spectrometric analysis. This method is pre-targeted, hence after searching for pre-assigned masses, it identifies those compounds that were pre-defined with available calibrants. Therefore, the scope for detecting novel toxins which are not included in the monitoring protocol are very limited. In addition to this, there is a poor comprehension of the toxicity of some marine toxin groups. Also, the validity of the current approach is questioned by the lack of sufficient calibrants, and by the insufficient coverage by current legislation of the toxins reported to be present in shellfish. As an example, tetrodotoxin, palytoxin analogs, or cyclic imines are mentioned as indicators of gaps in the system that require a solid comprehension to assure consumers are protected.
Funding Information
  • Xunta Galicia, Spain (GRC2013-016)
  • CDTI, Spain (IDI-20130304, AGL2012-40185-CO2-01, AGL2014-58210-R)
  • REA, EU (FP7/2007-2013) (312184 PHARMASEA)

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