A Pillararene-Based Ternary Drug-Delivery System with Photocontrolled Anticancer Drug Release
Abstract
A novel ternary drug delivery system (DDS) is constructed using a photodegradable anticancer prodrug (Py‐Cbl), a water‐soluble pillararene supramolecular container (WP6), and the diblock copolymer methoxy‐poly(ethylene glycol)114‐block‐poly(L‐lysine hydrochloride)200. This DDS successfully addresses three important issues: enhancement of the water solubility of the anticancer prodrug; controlled release of the anticancer drug; accurate and quantitative measurement of the drug release.Keywords
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