Production of antibodies against influenza virus by somatic cell hybrids between mouse myeloma and primed spleen cells.
Authors:
- H KoprowskiHKH Koprowski
- W GerhardWGW Gerhard
- C M CroceCCC M Croce
- 1 July 1977
- journal article
- research article
- Published by National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 74 (7) , 2985-2988
Abstract
We have produced somatic cell hybrids between mouse myeloma cells and spleen cells derived from a BALB/c mouse immunized with purified influenza virus. The hybrid cells were found to produce large amounts of antibodies specific for the hemagglutinin of the virus and were able to induce tumor formation when injected into BALB/c mice.Keywords
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