Further Investigation of Phenanthroindolizidine Alkaloids from Tylophora tanakae.

Authors:
  • MHMio Hirokawa
    Mio Hirokawa
  • TYTatsuo Yamauchi
    Tatsuo Yamauchi
  • KHKeiichi Honda
    Keiichi Honda
  • NHNanao Hayashi
    Nanao Hayashi
  • MIMineko Ishii
    Mineko Ishii
  • SISetsuko Imagawa
    Setsuko Imagawa
  • MIMichio Iwahana
    Michio Iwahana
Publisher website
Google Scholar
Abstract
In addition to ten alkaloids previously described, we have isolated two alkaloid N-oxides from Tylophora tanakae MAXIM. (Asclepiadaceae). Further, the polar fraction of the leaves and caules of this plant cultivated in a farm afforded two new polar alkaloids. The structures of the four products were determined. The relation between the structure and cytotoxic activity of this group of alkaloids is discussed.