The APC/C subunit APC7 promotes hepatocellular carcinoma progression by mediating ubiquitination and degradation of LATS1 to activate YAP/TAZ
Authors:
Open Access
- 23 March 2026
- journal article
- research article
- Published by Springer Nature in Biology Direct
- Vol. 21
Abstract
The anaphase-promoting complex/cyclosome (APC/C) is a multi-subunit E3 ubiquitin ligase critically involved in cell cycle regulation. However, the pathologKeywords
Funding Information
- National Natural Science Foundation of China (82130084)
- National Natural Science Foundation of China (82203336)
- the Project Program of the State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers (2025GTEP008)
- China Postdoctoral Science Foundation (2022TQ0088)
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