Stem cells and oral surgery: A systematic review
Authors:
Open Access
- 1 January 2019
- journal article
- review article
- Published by Medicina Oral, S.L. in Journal of Clinical and Experimental Dentistry
- Vol. 11 (12) , e1181-e1189
Abstract
Considering the structural loss that occurs after surgical procedures for cystic and tumoral pathology, in periodontitis, as well as the maxillary atrophy that determines the rehabilitation with dental implants, it is imperative to find satisfactory solutions. The opportunity provided by the findings in stem cells is a recent introduction in the field of oral surgery, based on the regenerative potential that these cells possess in order to restore defects at different levels of the oral cavity. The aim of this systematic review is to discover the real applications that stem cells may have in our treatments in the near future. We made a systematic review of the literature on the subject of stem cells to know the publications relating to them in the field of oral surgery since 2000. PRISMA statement was accomplished, as its official flow chart is used. This article draws clinical conclusions from basic research and those conducted in the first clinical cases to apply them in a short period of time to our patients in order to achieve excellence in regenerative therapies. To summarize, stem cells may be a turning point in tissue regeneration, though the major challenge is to overcome the remaining obstacles before they become a realistic therapeutic alternative. Key words:Stem cells, oral surgery, cell therapy, regeneration.Keywords
This publication has 51 references indexed in Scilit:
- Stem cell-delivery therapeutics for periodontal tissue regenerationBiomaterials, 2012
- In Vivo Comparison of Hard Tissue Regeneration with Human Mesenchymal Stem Cells Processed with Either the FICOLL Method or the BMAC MethodTissue Engineering Part C: Methods, 2010
- Bone morphogenetic proteins, cementogenesis, myoblastic stem cells and the induction of periodontal tissue regenerationCytokine & Growth Factor Reviews, 2009
- Putative stem cells in regenerating human periodontiumJournal of Periodontal Research, 2008
- Sinus augmentation using human mesenchymal stem cells loaded into a β-tricalcium phosphate/hydroxyapatite scaffoldOral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology, 2008
- Differentiation of Human Embryonic Stem Cells on Periodontal Ligament Fibroblasts In VitroArtificial Organs, 2007
- Assessment of cell proliferation during mandibular distraction osteogenesis in the maturing ratAmerican Journal of Orthodontics and Dentofacial Orthopedics, 2006
- Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined FactorsCell, 2006
- Early bone healing events in the human extraction socketInternational Journal of Oral and Maxillofacial Surgery, 2002
- Embryonic Stem Cell Lines Derived from Human BlastocystsScience, 1998