Diagnostic Performance of MRI Sequences for Evaluation of Dural Venous Sinus Thrombosis

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Abstract
OBJECTIVE. The purpose of this study is to assess the performance of routinely used MRI sequences with and without contrast enhancement in the diagnostic evaluation of dural venous sinus thrombosis (DVST). MATERIALS AND METHODS. We identified consecutive patients older than 18 years who underwent concurrent standardized brain MRI and contrast-enhanced (CE) MR venography (MRV) examinations for suspected DVST. The seven MRI sequences that were used (axial unenhanced T1-weighted, T1-weighted CE, T2-weighted, DWI, T2-weighted FLAIR, T2-weighted gradient-recalled echo [GRE], and sagittal 3D T1-weighted GRE CE sequences) were randomized, anonymized, and reviewed independently by two neuroradiologists who were blinded to the final diagnosis. Ten separate venous sinus segments were evaluated. CE MRV was the reference standard for determining the presence or absence of DVST, and it was performed using the following imaging parameters: TR/TE, 4.1–77/1.4–9.5; flip angle, 12–35°; and slice thickness, 0.8–1.4 mm. The ...

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