Conformations of linear DNA
Authors:
- 1 June 1997
- journal article
- research article
- Published by American Physical Society (APS) in Physical Review E
- Vol. 55 (6) , 7364-7368
Abstract
We examine the conformations of a model for underwound and overwound DNA. The molecule is represented as a cylindrically symmetric elastic string subjected to a stretching force and to constraints corresponding to a specification of the link number. We derive a fundamental relation between the Euler angles that describe the curve and the topological linking number. Analytical expressions for the spatial configurations of the molecule in the infinite-length limit are obtained. A unique configuration minimizes the energy for a given set of physical conditions. An elastic model incorporating thermal fluctuations provides excellent agreement with experimental results on the plectonemic transition.Keywords
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