Acquired immunity toTrichuris murisin the albino laboratory mouse
Author:
- 1 August 1967
- journal article
- research article
- Published by Cambridge University Press (CUP) in Parasitology
- Vol. 57 (3) , 515-524
Abstract
After infection with the nematodeTrichuris muris70–75% of mice of the Schofield strain developed an immunity to the parasite and eliminated the worms between the 16th and 19th days after infection. In these mice the acquired immunity persisted for at least 3 months and prevented the establishment of subsequent infections.In 25–30% of the mice immunity was not produced and infections developed into mature worms. These non-resistant mice remained susceptible to further infection.The development and action of the immune response were suppressed completely by the administration of cortisone acetate.Keywords
This publication has 8 references indexed in Scilit:
- Relationship of globule leucocytes to gastrointestinal nematodes in the sheep, and Nippostrongylus brasiliensis and Hymenolepis nana infections in ratsJournal of Comparative Pathology, 1966
- Use of cortisone derivatives to inhibit resistance to Nippostrongylus brasiliensis and to study the fate of parasites in resistant hostsParasitology, 1965
- Spontaneous Cure in Trichuris muris Infections in Albino Mice and Its Suppression by CortisoneJournal of Parasitology, 1963
- Experimental TrichiniasisAdvances in Parasitology, 1963
- Effect of Cortisone upon Infection with Trichuris muris in Albino MiceJournal of Parasitology, 1962
- Experimental Studies on Trichuris muris in Mice with an Appraisal of Its Use for Evaluating AnthelminticsJournal of Parasitology, 1962
- Experimental Trichuriasis. I. Antagonism between Trichuris muris and Aspiculuris tetraptera in the Albino MouseJournal of Parasitology, 1961
- An investigation on the life cycle of Trichuris murisParasitology, 1954