Altered Splicing of FGFR1 Is Associated with High Tumor Grade and Stage and Leads to Increased Sensitivity to FGF1 in Bladder Cancer
Authors:
- Darren C. TomlinsonDTDarren C. Tomlinson
- Margaret A. KnowlesMKMargaret A. Knowles
- 1 November 2010
- journal article
- Published by Elsevier in The American Journal of Pathology
- Vol. 177 (5) , 2379-2386
Abstract
No abstract availableKeywords
Funding Information
- Association for International Cancer Research (06-034)
This publication has 37 references indexed in Scilit:
- Fibroblast Growth Factor Receptor 1 Promotes Proliferation and Survival via Activation of the Mitogen-Activated Protein Kinase Pathway in Bladder CancerCancer Research, 2009
- Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in miceJournal of Clinical Investigation, 2009
- FGF5 as an oncogenic factor in human glioblastoma multiforme: autocrine and paracrine activitiesOncogene, 2008
- Cancer Statistics, 2008CA: A Cancer Journal for Clinicians, 2008
- FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancerThe Journal of Pathology, 2007
- Knockdown by shRNA identifies S249C mutant FGFR3 as a potential therapeutic target in bladder cancerOncogene, 2007
- Receptor Specificity of the Fibroblast Growth Factor FamilyJournal of Biological Chemistry, 2006
- Oncogenic properties of the mutated forms of fibroblast growth factor receptor 3bCarcinogenesis, 2005
- Alternative Splicing of Fibroblast Growth Factor Receptor 3 Produces a Secreted Isoform That Inhibits Fibroblast Growth Factor–Induced Proliferation and Is Repressed in Urothelial Carcinoma Cell LinesCancer Research, 2005
- Basic fibroblast growth factor and fibroblast growth factor receptor I are implicated in the growth of human astrocytomasJournal of Neuro-Oncology, 1994