10‘-Hydroxyusambarensine, a New Antimalarial Bisindole Alkaloid from the Roots of Strychnos usambarensis

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Abstract
Reinvestigation of Strychnos usambarensis Gilg resulted in the isolation of a tertiary phenolic bisindole alkaloid, 10‘-hydroxyusambarensine (1), which was identified by detailed spectroscopic methods. Compound 1 was moderately active against two strains of Plasmodium falciparum in vitro.

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