Potential of stem cell based therapy and tissue engineering in the regeneration of the central nervous system
Authors:
- Yihua AnYAYihua An
- Kent K S TsangKTKent K S Tsang
- Han ZhangHZHan Zhang
- 30 May 2006
- journal article
- review article
- Published by IOP Publishing in Biomedical Materials
- Vol. 1 (2) , R38-R44
Abstract
The insufficiency of self-repair and regeneration of the central nervous system (CNS) leads to difficulty of rehabilitation of the injured brain. In the past few decades, the significant progress in cell therapy and tissue engineering has contributed to the functional recovery of the CNS to a great extent. The present review focuses on the potential role of stem cell based therapy and tissue engineering in the regeneration of the CNS.Keywords
This publication has 97 references indexed in Scilit:
- Stem and progenitor cell–based therapy of the human central nervous systemNature Biotechnology, 2005
- Rescue and sprouting of motoneurons following ventral root avulsion and reimplantation combined with intraspinal adeno-associated viral vector-mediated expression of glial cell line-derived neurotrophic factor or brain-derived neurotrophic factorExperimental Neurology, 2004
- Constitutive and Induced Neurogenesis in the Adult Mammalian Brain: Manipulation of Endogenous Precursors toward CNS RepairDevelopmental Neuroscience, 2004
- Imaging of Stem Cell Recruitment to Ischemic Infarcts in a Murine ModelStroke, 2004
- Human Neural Stem Cell Transplantation Promotes Functional Recovery in Rats With Experimental Intracerebral HemorrhageStroke, 2003
- Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosisNature, 2003
- Human neural stem cells improve cognitive function of aged brainNeuroReport, 2001
- Mammalian Neural Stem CellsScience, 2000
- Out of Eden: Stem Cells and Their NichesScience, 2000
- Hydrogels Containing Peptide or Aminosugar Sequences Implanted into the Rat Brain: Influence on Cellular Migration and Axonal GrowthExperimental Neurology, 1997