Ochratoxin A: Inhibition of Mitochondrial Respiration
Authors:
- 29 May 1970
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 168 (3935) , 1102-1103
Abstract
Ochratoxin A is a fungal metabolite which induces pathological changes in animals. The toxin was isolated from cultures of Aspergillus ochraceus and purified by thin-layer chromatography. Ochratoxin A and one of its hydrolysis products, dihydroisocoumarin, severely inhibited coupled respiration when applied at low concentration to rat liver mitochondria.Keywords
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