Design, synthesis and anticancer evaluation of novel spirobenzo[h]chromene and spirochromane derivatives with dual EGFR and B-RAF inhibitory activities

This publication has 47 references indexed in Scilit:

• Intrinsic caspase-8 activation mediates sensitization of erlotinib-resistant tumor cells to erlotinib/cell-cycle inhibitors combination treatment
  Cell Death & Disease, 2012
• Synthesis and antitumor studies of novel benzopyrano-1,2,3-selenadiazole and spiro[benzopyrano]-1,3,4-thiadiazoline derivatives
  Medicinal Chemistry Research, 2012
• Discovery, Synthesis, and Pharmacological Evaluation of Spiropiperidine Hydroxamic Acid Based Derivatives as Structurally Novel Histone Deacetylase (HDAC) Inhibitors
  Journal of Medicinal Chemistry, 2011
• Targeted Inhibition of Kinases in Cancer Therapy
  Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine, 2010
• Synthesis and evaluation of novel stearoyl-CoA desaturase 1 inhibitors: 1′-{6-[5-(pyridin-3-ylmethyl)-1,3,4-oxadiazol-2-yl]pyridazin-3-yl}-3,4-dihydrospiro[chromene-2,4′-piperidine] analogs
  European Journal of Medicinal Chemistry, 2010
• Synthesis and cyclisation of 1,4-disubstituted semicarbazides
  Natural Product Research, 2010
• Targeting of the Akt-Nuclear Factor-κB Signaling Network by [1-(4-Chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol (OSU-A9), a Novel Indole-3-Carbinol Derivative, in a Mouse Model of Hepatocellular Carcinoma
  Molecular Pharmacology, 2009
• Sensitivity of breast cancer cells to erlotinib depends on cyclin-dependent kinase 2 activity
  Molecular Cancer Therapeutics, 2007
• Synthesis and Structure−Activity Relationships of Parasiticidal Thiosemicarbazone Cysteine Protease Inhibitors against Plasmodium falciparum, Trypanosoma brucei, and Trypanosoma cruzi
  Journal of Medicinal Chemistry, 2004
• Eine einfache Synthese von 4-Chromanonen
  Synthesis, 1978