Orthogonal Wavefield Synthesis for Nonnegative Photoacoustic Imaging

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Abstract
Photoacoustic tomography has developed rapidly in recent years and holds great potential for applications in the biomedical field. In photoacoustic tomography, the quality of the final reconstructed image mainly depends on the choice of reconstruction algorithm. However, traditional filtered back projection algorithms may introduce negative artifacts into the final reconstructed images due to the finite bandwidth of ultrasound transducers. To address the issue of negative artifacts, we propose a photoacoustic imaging method based on the virtual orthogonal wave field. This method converts the original photoacoustic signals into pairs of virtual orthogonal signals, constructs the real and imaginary parts of the photoacoustic complex signal from them and extracts the virtual photoacoustic envelope, thereby obtaining a reconstruction image without negative artifacts. In this work, we propose the theory of the virtual orthogonal wave field. By combining the point spread function based on spherical harmonics with the theory of the virtual orthogonal wave field, the point spread function of the virtual orthogonal wave field method is derived, we explain the theoretical basis for non-negative imaging using this method. The result of simulations and experiments demonstrates that this method can effectively eliminate negative artifacts and improve image fidelity.
Funding Information
  • Sichuan Science and Technology Program (Grant No. 2023ZYD0018)
  • National Natural Science Foundation of China (Grant No. 12204242)
  • Natural Science Foundation of Jiangsu Province (Grant No. BK20210323)

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