Storage of Platelet Concentrates at 22°C
Authors:
Open Access
- 1 April 1970
- journal article
- Published by American Society of Hematology in Blood
- Vol. 35 (4) , 549-557
Abstract
A technique has been proposed which allows easy preparation of platelet concentrates within a closed, sterile system and maximal utilization of other blood components. Lifespan studies have been performed to demonstrate the viability of platelets prepared in this manner. Such concentrates can be stored for as long as three days with adequate maintenance of viability for tranfusion purposes if certain technical requirements are met. Important among these are attention to concentrate volume and pH; agitation of the concentrate is helpful for maintenance of viability. Twelve studies in thrombocytopenic recipients suggest that stored concentrates will be safe and effective in transfusion practice.Keywords
This publication has 6 references indexed in Scilit:
- The effect of platelet age on platelet adherence to collagenJournal of Clinical Investigation, 1968
- A Simple Method for Obtaining Platelet Concentrates Free of AggregatesTransfusion, 1968
- Cryoprecipitate Concentrates of Factor VIII for Surgery in HemophiliacsAnnals of Internal Medicine, 1968
- Pooling of platelets in the spleen: role in the pathogenesis of "hypersplenic" thrombocytopenia.Journal of Clinical Investigation, 1966
- Immunological Considerations Attending Platelet TransfusionTransfusion, 1966
- Effect of Storage up to 48 Hours on Response to Transfusions of Platelet Rich PlasmaTransfusion, 1964