Kaempferol Regulates the Expression of Airway MUC5AC Mucin Gene via IκBα-NF-κB p65 and p38-p44/42-Sp1 Signaling Pathways
Open Access
- 1 May 2021
- journal article
- research article
- Published by The Korean Society of Applied Pharmacology in Biomolecules & Therapeutics
- Vol. 29 (3) , 303-310
Abstract
Xin Li, Fengri Jin, Hyun Jae Lee,* and Choong Jae Lee,*. Biomolecules & Therapeutics 2021;29:303-10. https://doi.org/10.4062/biomolther.2020.149Keywords
Funding Information
- National Research Foundation of Korea (NRF-2014R1A6A1029617, NRF-2017R1C1B1005126)
- Ministry of Education
This publication has 40 references indexed in Scilit:
- Dietary Kaempferol Suppresses Inflammation of Dextran Sulfate Sodium-Induced Colitis in MiceDigestive Diseases and Sciences, 2011
- Kaempferol and quercetin, essential ingredients in Ginkgo biloba extract, inhibit interleukin‐1β‐induced MUC5AC gene expression in human airway epithelial cellsPhytotherapy Research, 2009
- Regulation of Airway MUC5AC Expression by IL-1β and IL-17A; the NF-κB ParadigmThe Journal of Immunology, 2009
- Genistein and curcumin suppress epidermal growth factor‐induced MUC5AC mucin production and gene expression from human airway epithelial cellsPhytotherapy Research, 2009
- Effects of baicalin and wogonin on mucin release from cultured airway epithelial cellsPhytotherapy Research, 2007
- Distinctive Epidermal Growth Factor Receptor/Extracellular Regulated Kinase-Independent and -Dependent Signaling Pathways in the Induction of Airway Mucin 5B and Mucin 5AC Expression by Phorbol 12-Myristate 13-AcetateThe American Journal of Pathology, 2007
- Treatment of airway mucus hypersecretionAnnals of Medicine, 2006
- Phosphodiesterase 4 inhibition decreases MUC5AC expression induced by epidermal growth factor in human airway epithelial cellsThorax, 2005
- Pranlukast Inhibits NF-κB Activation and MUC2 Gene Expression in Cultured Human Epithelial CellsPharmacology, 2005
- PMA Induces the MUC5AC Respiratory Mucin in Human Bronchial Epithelial Cells, via PKC, EGF/TGF-α, Ras/Raf, MEK, ERK and Sp1-dependent MechanismsJournal of Molecular Biology, 2004