Polyester Vascular Graft Material and Risk for Intracavitary Thoracic Vascular Graft Infection1

Authors:
  • TSTiziano A. Schweizer
    Tiziano A. Schweizer
  • SSSrikanth Mairpady Shambat
    Srikanth Mairpady Shambat
  • VHVanina Dengler Haunreiter
    Vanina Dengler Haunreiter
  • CMCarlos A. Mestres
    Carlos A. Mestres
  • AWAlberto Weber
    Alberto Weber
  • FMFrancesco Maisano
    Francesco Maisano
  • AZAnnelies S. Zinkernagel
    Annelies S. Zinkernagel

Abstract
Prosthetic vascular graft infections of the thoracic aorta are rare but can be fatal. Our comparison of collagen- and gelatin-coated grafts showed that collagen-coated grafts were associated with increased biofilm formation and bacterial adherence in vitro and with higher rates of perioperative vascular graft infections in vivo.

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