Polymorphisms for Aromatic Amine Metabolism in Humans: Relevance for Human Carcinogenesis

Authors:
  • FKFred F. Kadlubar
    Fred F. Kadlubar
  • MBMary Ann Butler
    Mary Ann Butler
  • KKKeith R. Kaderlik
    Keith R. Kaderlik
  • HCHsien-Chang Chou
    Hsien-Chang Chou
  • NLNicholas P. Lang
    Nicholas P. Lang
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Abstract
The metabolic pathways associated with carcinogenic aromatic amines in humans provide an excellent example of polymorphisms that appear to be relevant to human carcinogenesis. In this regard, the N-acetylation of arylamines and the O-acetylation of their ...