Atrial dysfunction as a marker of iron cardiotoxicity in thalassemia major
Authors:
- W. LiWLW. Li
- T. CoatesTCT. Coates
- J. C. WoodJWJ. C. Wood
Open Access
- 1 February 2008
- journal article
- Published by Ferrata Storti Foundation (Haematologica) in Haematologica
- Vol. 93 (2) , 311-312
Abstract
We measured left atrial size and function from biplane MRI data in 62 adults with thalassemia major. Age-adjusted left atrial ejection fraction was depressed in 7 out of 20 subjects having T2* < 10 ms. Left atrial size, left ventricular size and cardiac output fell with cardiac iron loading, representing increased cardiac or peripheral vascular stiffness.Keywords
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