The Pancreas and Known Factors of Acute Pancreatitis
Open Access
- 22 September 2022
- journal article
- review article
- Published by MDPI AG in Journal of Clinical Medicine
- Vol. 11 (19) , 5565
Abstract
Pancreatitis is regarded by clinicians as one of the most complicated and clinically challenging of all disorders affecting the abdomen. It is classified on the basis of clinical, morphological, and histological criteria. Causes of acute pancreatitis can easily be identified in 75–85% of patients. The main causes of acute, recurrent acute, and chronic pancreatitis are gallstone migration and alcohol abuse. Other causes are uncommon, controversial, or unexplained. For instance, cofactors of all forms of pancreatitis are pancreas divisum and hypertriglyceridemia. Another factor that should be considered is a complication of endoscopic retrograde cholangiopancreatography: post-endoscopic retrograde cholangiopancreatography acute pancreatitis. The aim of this study is to present the known risk factors for acute pancreatitis, beginning with an account of the morphology, physiology, and development of the pancreas.Keywords
This publication has 112 references indexed in Scilit:
- Santorinicele without pancreas divisum pathophysiology: initial clinical and radiographic investigationsBMC Gastroenterology, 2013
- Pre-Study protocol MagPEP: a multicentre randomized controlled trial of magnesium sulphate in the prevention of post-ERCP pancreatitisBMC Gastroenterology, 2013
- Congenital Variants and Anomalies of the Pancreas and Pancreatic Duct: Imaging by Magnetic Resonance Cholangiopancreaticography and Multidetector Computed TomographyKorean Journal of Radiology, 2013
- Increased Activation of Hereditary Pancreatitis-associated Human Cationic Trypsinogen Mutants in Presence of Chymotrypsin CJournal of Biological Chemistry, 2012
- Cathepsin L Inactivates Human Trypsinogen, Whereas Cathepsin L-Deletion Reduces the Severity of Pancreatitis in MiceGastroenterology, 2010
- Pathways to Injury in Chronic Pancreatitis: Decoding the Role of the High-Risk SPINK1 N34S Haplotype Using Meta-AnalysisPLOS ONE, 2008
- Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitisNature Genetics, 2007
- Morphologic characterization of early ligation–induced acute pancreatitis in ratsThe American Journal of Surgery, 2007
- Chymotrypsin C (caldecrin) promotes degradation of human cationic trypsin: Identity with Rinderknecht's enzyme YProceedings of the National Academy of Sciences, 2007
- A degradation-sensitive anionic trypsinogen (PRSS2) variant protects against chronic pancreatitisNature Genetics, 2006